The new technology uses an engineered protein that, according to a report by Liu and 10 others today in the journal Nature, can transform any single DNA letter into any other, as well as add or delete longer stretches. In fact, Liu claims it’s capable of repairing nearly any of the 75,000 known mutations that cause inherited disease in humans.

https://www.technologyreview.com/s/614599/the-newest-gene-editor-radically-improves-on-crispr/

https://www.nature.com/articles/s41586-019-1711-4

https://blog.addgene.org/prime-editing-crisp-cas-reverse-transcriptase